Syntheses of Aminoacid Derivatives and Their Biological Activities.I. Anti-Influenza Activity
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منابع مشابه
Anti-Influenza Activity of C60 Fullerene Derivatives
The H1N1 influenza A virus, which originated in swine, caused a global pandemic in 2009, and the highly pathogenic H5N1 avian influenza virus has also caused epidemics in Southeast Asia in recent years. Thus, the threat from influenza A remains a serious global health issue, and novel drugs that target these viruses are highly desirable. Influenza A RNA polymerase consists of the PA, PB1, and P...
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Aseries of piperidine derivatives was synthesis by the reaction between substituted benzaldhyde ,pentanone-3,and ammonium acetate by refluxining for 1-2 hr in ethanol and the derivatives refluxed with (4,4'-Diaminodiphenyl sulphone) yielded bispiperidine ,the structures of the synthesized compounds were confirmed by spectroscopy analysis , The reported compounds were screened for their antibact...
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Aseries of piperidine derivatives was synthesis by the reaction between substituted benzaldhyde ,pentanone-3,and ammonium acetate by refluxining for 1-2 hr in ethanol and the derivatives refluxed with (4,4'-Diaminodiphenyl sulphone) yielded bispiperidine ,the structures of the synthesized compounds were confirmed by spectroscopy analysis , The reported compounds were screened for their antibact...
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Two novel andrographolide analogues with the structural motif of Δ(8,17)-alkene exo-to-endo isomerization, AI78 and AI89, were semi-synthesized firstly. Two series of derivatives were designed and synthesized based on the synthetic pathway (including series I: olefin isomerizing to endocyclic Δ(8,9) and series II: olefin isomerizing to endocyclic Δ(7,8)). The anti-influenza virus activity in vi...
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Substituted 1,4-diaza-1,3-butadienes with 2 equivalents of 1,4-naphthoquinone in presence of ethanol or benzene produce corresponding substituted bisindoletetrones via criss-cross cycloaddition reaction. The chemical structure was confirmed by elemental and spectral analysis. Biological activity against some micro-organisms was tested.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1975
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.95.4_397